Hydrogen Bromide → HCID 67359866, compound

HRID 473467Notes

Reaction equation

HRID 473467 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:11](=[O:12])[C:10]3[CH:13]=[CH:14][CH:15]=[C:16]([O:17]C)[C:9]=3[CH2:8][CH2:7][C:6]=2[CH:19]=1.Br>C(O)(=O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:11](=[O:12])[C:10]3[CH:13]=[CH:14][CH:15]=[C:16]([OH:17])[C:9]=3[CH2:8][CH2:7][C:6]=2[CH:19]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 67360944HCID 67360944, compound

Product 1

HCID 67359866HCID 67359866, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

For the synthesis of the title compound, 1.0 (4.87 mmol) g of 8-chloro-1-methoxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one, 10 ml of HBr (48%, aqueous) and 10 ml of glacial acetic acid are employed in method L. Yield: 95%; m.p.: 185° C.; GC 15.2 min; C15H11ClO2 (Mr=258.71)

Sources & evidence

ORD record
ord-dd806ffd15d54fc5918262bc2c5aa02a
Source dataset
uspto-grants-2014_01
Patent number
US08633312B2

Reaction notes

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