Stannous chloride dihydrate → 8-Amino-3-(2-methoxyphenylamino)-6H-dibenzo[b,e]oxepin-11-one

HRID 473491Notes

Reaction equation

HRID 473491 reaction equation
O.O.[Sn](Cl)Cl.[CH3:6][O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15]1[CH:16]=[CH:17][C:18]2[C:24](=[O:25])[C:23]3[CH:26]=[CH:27][C:28]([N+:30]([O-])=O)=[CH:29][C:22]=3[CH2:21][O:20][C:19]=2[CH:33]=1>C(O)C>[NH2:30][C:28]1[CH:27]=[CH:26][C:23]2[C:24](=[O:25])[C:18]3[CH:17]=[CH:16][C:15]([NH:14][C:9]4[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=4[O:7][CH3:6])=[CH:33][C:19]=3[O:20][CH2:21][C:22]=2[CH:29]=1

Participants

4

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 673629583-(2-Methoxyphenylamino)-8-nitro-6H-dibenzo[b,e]oxepin-11-one

Product 1

HCID 452807438-Amino-3-(2-methoxyphenylamino)-6H-dibenzo[b,e]oxepin-11-one

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In accordance with general method Y, 0.10 g (0.44 mmol) of tin(II) chloride dihydrate is dissolved in 15 ml of ethanol, and 0.04 g (0.10 mmol) of (14) is added. Yield: 0.0046 g (13.3%); melting point: 68.4° C.; C21H18N2O3 (Mr=346.39); LC 18.55 min

Workup

  1. customLC 18.55 min

Sources & evidence

ORD record
ord-88f3c02542b0478aa4b53491bfa375c2
Source dataset
uspto-grants-2014_01
Patent number
US08633312B2

Reaction notes

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