反应详情

温度

40 °C

In this example, 3.39 g of ethyl (N-methyl-3-trifluoromethylbenzylsulfonamido)acetate was ground to a powder and combined with about 50 ml of ammonium hydroxide at room temperature. The reaction mixture was heated to about 40° C. and maintained at this temperature for about three hours. The precipitate was collected, washed with water and triturated with ethyl ether to afford 1.4 g of white solid; m.p. 156° to 159° C.

1. temperaturemaintained at this temperature for about three hours
2. customThe precipitate was collected
3. washwashed with water
4. customtriturated with ethyl ether