Acetonitrile → N,N-Dipropyl-2,3,5,6,7,8-hexahydronaphtho[2,3-b]furan-7-amine

HRID 476754Notes

Reaction equation

HRID 476754 reaction equation
[CH2:1](I)[CH2:2][CH3:3].[C:5](=O)([O-])[O-].[K+].[K+].Cl.[NH2:12][CH:13]1[CH2:25][C:24]2[C:16](=[CH:17][C:18]3[CH2:22][CH2:21][O:20][C:19]=3[CH:23]=2)[CH2:15][CH2:14]1.[C:26](#N)[CH3:27]>>[CH2:1]([N:12]([CH:13]1[CH2:25][C:24]2[C:16](=[CH:17][C:18]3[CH2:22][CH2:21][O:20][C:19]=3[CH:23]=2)[CH2:15][CH2:14]1)[CH2:5][CH2:26][CH3:27])[CH2:2][CH3:3]

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 11430Potassium CarbonateHCID 336431-IodopropaneHCID 19838440HCID 19838440, compound

Product 1

HCID 115007N,N-Dipropyl-2,3,5,6,7,8-hexahydronaphtho[2,3-b]furan-7-amine

Procedure

13.4 g of propyl iodide and 11 g of potassium carbonate are added to 1.5 g of the compound of Example 2 dissolved in 10 ml of acetonitrile.

Sources & evidence

ORD record
ord-bd2a45f50e4d41ec95e6b7aa583f43de
Source dataset
uspto-grants-1989_12
Patent number
US04885373

Reaction notes

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