Triethylamine → HCID 14390154, compound

HRID 476766Notes

Reaction equation

HRID 476766 reaction equation
Cl.[NH2:2][CH:3]1[CH2:15][C:14]2[C:6](=[CH:7][C:8]3[CH2:12][CH2:11][O:10][C:9]=3[CH:13]=2)[CH2:5][CH2:4]1.C(N(CC)CC)C.[F:23][C:24]([F:31])([F:30])[C:25](OCC)=[O:26]>CO>[F:23][C:24]([F:31])([F:30])[C:25]([NH:2][CH:3]1[CH2:15][C:14]2[C:6](=[CH:7][C:8]3[CH2:12][CH2:11][O:10][C:9]=3[CH:13]=2)[CH2:5][CH2:4]1)=[O:26]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 9794Ethyl trifluoroacetateHCID 19838440HCID 19838440, compound

Product 1

HCID 14390154HCID 14390154, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture containing 5 g of the compound of Example 2, 3.35 ml of triethylamine and 4 ml of ethyl trifluoroacetate in 7 ml of methanol is stirred for 4 hours at room temperature. The mixture is then evaporated to dryness and the dry residue obtained is recrystallized in isopropyl ether.

Workup

  1. customThe mixture is then evaporated to dryness
  2. customthe dry residue obtained
  3. customis recrystallized in isopropyl ether

Sources & evidence

ORD record
ord-6a495e977a0244f9891818025b6f35bd
Source dataset
uspto-grants-1989_12
Patent number
US04885373

Reaction notes

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