反应详情

8.4 g (35 mMol) of 4-[N-(4-chloro-benzyl)-amino]-cyclohexanone are dissolved in 50 ml of absolute dimethylformamide and, after the addition of 2.6 g (18.7 mMol) of potassium carbonate, 5.0 g (35 mMol) of methyliodide are added dropwise at 25°-30° C. After standing overnight the mixture is concentrated, mixed with water and extracted with chloroform. The extracts are dried and concentrated.

1. additionare added dropwise at 25°-30° C
2. concentrationthe mixture is concentrated
3. additionmixed with water
4. extractionextracted with chloroform
5. customThe extracts are dried
6. concentrationconcentrated