Benzenamine, 2-chloro-5-(trifluoromethyl)- → 2,6-Dichloro-3-(trifluoromethyl)aniline

HRID 477257Notes

Reaction equation

HRID 477257 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:6]([C:9]([F:12])([F:11])[F:10])=[CH:5][C:3]=1[NH2:4].[Cl:13]N1C(=O)CCC1=O>>[Cl:13][C:5]1[C:6]([C:9]([F:10])([F:11])[F:12])=[CH:7][CH:8]=[C:2]([Cl:1])[C:3]=1[NH2:4]

Participants

3

Reactant 2

HCID 8475Benzenamine, 2-chloro-5-(trifluoromethyl)-HCID 31398Chlorosuccinimide

Product 1

HCID 134704732,6-Dichloro-3-(trifluoromethyl)aniline

Procedure

This material was prepared by chlorination of 2-chloro-5-trifluoromethylaniline with N-chlorosuccinimide followed by chromatographic purification. The product was isolated as a yellow oil which was characterized by IR and 1H NMR spectroscopy and combustion analysis.

Workup

  1. customfollowed by chromatographic purification
  2. customThe product was isolated as a yellow oil which

Sources & evidence

ORD record
ord-f9c02b53318d4f1e9ac145e0e7814ec2
Source dataset
uspto-grants-1989_12
Patent number
US04886883

Reaction notes

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