反应详情

Acetyl chloride (12.57 g) in methylene chloride (30 ml) was added to the product of stage (a) (30 g) in triethylamine (25 ml) and methylene chloride (300 ml) at 0° C., and the mixture was stirred for 30 minutes. Then 1N sodium hydroxide was added, and the solution was extracted with methylene chloride. On drying, and recrystallisation from ethyl acetate, 33 g of the desired product, mp 146° C., were obtained.

1. extractionthe solution was extracted with methylene chloride
2. customOn drying
3. customrecrystallisation from ethyl acetate, 33 g of the desired product, mp 146° C.
4. customwere obtained