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HRID478748

反应详情

EQUATION

反应方程式

HRID 478748 的结构方程式

REACTANTS

反应物

3
结构：CC(C)[N-]C(C)C.[Li+]
HCID2724682

2-Propanamine, N-(1-methylethyl)-, lithium salt

C6H14LiN

结构：O=Cc1cccnc1Nc1cccc([N+](=O)[O-])c1
HCID12114952

未命名化合物

结构：Cc1ccc2cc(CCCc3ccncc3)c(=O)n(-c3cccc([N+](=O)[O-])c3)c2n1
HCID18002612

未命名化合物

PRODUCTS

生成物

1
结构：O=c1c(CCCCc2ccccn2)cc2cccnc2n1-c1cccc([N+](=O)[O-])c1
HCID12074624

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The procedure of Example 1 was repeated using 2-(3-nitrophenylamino)nicotinaldehyde (1.0 eq.), ethyl 6-(pyridin-2-yl)hexanoate (2.0 eq., prepared in Synthetic Example 11) and LDA (2.0 eq.) to obtain 1-(3-nitrophenyl)-3-[4-(pyridin-2-yl)butyl]-1,8-naphthyridin-2(1H)-one, mp 163 to 165° C./DMF, wherein the product was purified through silica gel column chromatography and recrystallization.