Diglyme → HCID 178418794, compound

HRID 479436Notes

Reaction equation

HRID 479436 reaction equation
[CH2:1]([O:3][C:4](=[O:11])[C:5]([N:7](C=O)[NH2:8])=[NH:6])[CH3:2].[CH3:12]OCCOCCOC>>[CH2:1]([O:3][C:4]([C:5]1[N:6]=[CH:12][NH:8][N:7]=1)=[O:11])[CH3:2]

Participants

3

Reactant 2

HCID 8150DiglymeHCID 86590617(N-Formylhydrazino)-imino acetic acid ethyl ester

Product 1

HCID 178418794HCID 178418794, compoundYield 85%

Procedure

A suspension of (N-Formylhydrazino)-imino acetic acid ethyl ester (9.62 g, 60.4 mmol) in diglyme (40 ml) was refluxed for 30 minutes. After cooling, the precipitated crystal was collected by filteration and washed with hexane to give 1H-1,2,4-triazol-3-carboxylic acid ethyl ester (7.28 g). Yield: 85%.

Workup

  1. temperaturewas refluxed for 30 minutes
  2. temperatureAfter cooling
  3. customthe precipitated crystal was collected by filteration
  4. washwashed with hexane

Sources & evidence

ORD record
ord-eca22cda00504afa90abc92f0f741e52
Source dataset
uspto-grants-2003_11
Patent number
US06645956B1

Reaction notes

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