反应详情

To the commercially available 6-bromo-naphthalene-2-ol (1) (1 equi.) and benzyl bromide (2) (1 equi.) in DMF (3mL/mmole), cesium carbonate (1.25 equi.) was added at room temperature. The reaction mixture was stirred at that temperature for 24 h, quenched with water, extracted with ethyl acetate:hexane (1:1), washed with brine, over MgSO4, and concentrated in vacuo.

1. customquenched with water
2. extractionextracted with ethyl acetate:hexane (1:1)
3. washwashed with brine, over MgSO4
4. concentrationconcentrated in vacuo