反应详情

Using 2.2 g of methyl 4-bromomethylphenylacetate, 1.5 g of 1-(2-piperazinyl)piperazine, 1.9 ml of triethylamine, and 70 ml of dioxane, the reaction procedure of Example 2 was otherwise repeated and the reaction product was converted to the hydrochloride using 2N-hydrochloric acid and recrystallized from ethanol-ether to provide 1.1 g of the title compound melting at 214° C.-216° C.

1. customthe reaction procedure of Example 2
2. customrecrystallized from ethanol-ether