Diethyl Ether → HCID 54302294, compound

HRID 483108Notes

Reaction equation

[N+:1]([CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)([O-:3])=[O:2].C(N(CC)CC)C.C(OCC)(=O)C[SH:21].[CH3:26][CH2:27][O:28][CH2:29][CH3:30]>>[CH2:27]([O:28][C:29](=[S:21])[CH2:30][CH:5]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:4][N+:1]([O-:3])=[O:2])[CH3:26]

Participants

Reactant 4

HCID 3283Diethyl Ether

HCID 7626Beta-Nitrostyrene

HCID 8471Triethylamine

HCID 12185Ethyl Thioglycolate

Product 1

HCID 54302294HCID 54302294, compound

Procedure

To a solution of beta-nitrostyrene (447 mg) in ether (10 ml) are added triethylamine (42 l) and ethyl thioglycolate (0.33 ml). After 30 minutes' stirring, the mixture is concentrated to give (1-phenyl-2-nitroethyl)thioacetic acid ethyl ester (718 mg).

Workup

concentrationthe mixture is concentrated

Sources & evidence

ORD record: ord-c89227822d924da78b9cd102179ba460
Source dataset: uspto-grants-1986_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04578378

Reaction notes

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