Hydrochloric Acid → HCID 20299615, compound

HRID 483321Notes

Reaction equation

HRID 483321 reaction equation
[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[ClH:11]>O>[ClH:11].[ClH:11].[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15600Decane

Product 1

HCID 20299615HCID 20299615, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The procedure is as in Example 1, but starting from 8-acetylamino-8-acetylaminomethyl-tricyclo[5.2.1.0/2,6]decane (1.97 g), in the form of the exo racemate, in a 6N solution (50 cc) of hydrochloric acid in water for 24 hours under reflux. Taking up the residue from the evaporation in ethanol (20 cc) and diethyl ether (80 cc), 6-amino-8-aminomethyl-tricyclo[5.2.1.0/2,6]decane dihydrochloride (1.26 g), is obtained, as the exo racemate, in the form of white crystals which melt at 273°-5° C.

Workup

  1. customTaking up the residue from the evaporation in ethanol (20 cc)

Sources & evidence

ORD record
ord-362c0302337641439ebc3eeb80673a77
Source dataset
uspto-grants-1993_07
Patent number
US05225207

Reaction notes

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