反应详情

Scheme IIIb, step C: 4-(3-Aminopropyl)-2-fluorobenzenecarbonitrile (1.1 g, 6.17 mmol) and boron dimethylsulfide 2M in THF (6.2 mL, 12.34 mmol) were combined and reduction was carried out in a manner analogous to the procedure described in example 6 to provide the intermediate title compound, 3-[4-(aminomethyl)-3-fluorophenyl]propylamine dihydrochlorde, (1.15 g, 73%) as a dihydrochloride salt. Electron spray M.S. 183 (M*+H).