Hydrochloric Acid → HCID 67856276, compound

HRID 483807Notes

Reaction equation

HRID 483807 reaction equation
[CH3:1][N:2]([NH:12][C@H:13]([C:17]([NH:19]C(OC(C)(C)C)=O)=[O:18])[CH2:14][S:15][CH3:16])[C:3]1[CH:11]=[CH:10][C:6]2[O:7][CH2:8][O:9][C:5]=2[CH:4]=1.[ClH:27]>C(OCC)(=O)C>[ClH:27].[CH3:1][N:2]([NH:12][C@H:13]([C:17]([NH2:19])=[O:18])[CH2:14][S:15][CH3:16])[C:3]1[CH:11]=[CH:10][C:6]2[O:7][CH2:8][O:9][C:5]=2[CH:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67856345HCID 67856345, compound

Product 1

HCID 67856276HCID 67856276, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

After 6.323 g (17.183 mmol) of (N-methyl-1,3-benzodioxol-5-ylamino)-N-t-butoxycarbonyl-S-methyl-L-cysteinamide were dissolved in 100 ml of ethyl acetate, an excess of hydrochloric acid was ebulated. A precipitate so precipitated was collected by filtration, washed with ether, and then dried under reduced pressure, whereby 4.5 g of (N-methyl-1,3-benzodioxol-5-ylamino)-S-methyl-L-cysteinamide hydrochloride were obtained (yield: 86%).

Workup

  1. customA precipitate so precipitated
  2. filtrationwas collected by filtration
  3. washwashed with ether
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-1d8e72c3ac9f4489aae533ba2928e437
Source dataset
uspto-grants-1993_07
Patent number
US05227398

Reaction notes

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