反应详情

The title compound was prepared by the method of Example 9 using 10.5 g of the product compound of Example 10, except that no hydrochloric acid was added during hydrogenation. The crude product was dissolved in methanol and acidified with HCl in isopropyl alcohol. Addition of diethyl ether induced precipitation of 11.6 g of the title compound. Structure assignment was supported by the nmr spectrum and by elemental analysis.

1. additionwas added during hydrogenation
2. customprecipitation of 11.6 g of the title compound