Hydrochloric Acid → 1-(3-Diethylaminopropyl)-3,5-diaminoindazole trihydrochloride

HRID 484844Notes

Reaction equation

HRID 484844 reaction equation
[CH2:1]([N:3]([CH2:18][CH3:19])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][C:12]([NH2:16])=[CH:13][CH:14]=2)[C:9]([NH2:17])=[N:8]1)[CH3:2].[ClH:20].C(OCC)C>C(O)C>[ClH:20].[ClH:20].[ClH:20].[CH2:18]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][C:12]([NH2:16])=[CH:13][CH:14]=2)[C:9]([NH2:17])=[N:8]1)[CH3:19]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 201358391-[3-(Diethylamino)propyl]-1H-indazole-3,5-diamine

Product 1

HCID 201358381-(3-Diethylaminopropyl)-3,5-diaminoindazole trihydrochloride

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 15 ml of absolute ethyl alcohol was dissolved 0.6 g of 1-(3-diethylaminopropyl)-3,5-diaminoindazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. To the solution was added anhydrous diethyl ether to separate crystals. Then the crystals were obtained by filtration and dried to give 1-(3-diethylaminopropyl)-3,5-diaminoindazole trihydrochloride having the following analytical value.

Workup

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThen the crystals were obtained by filtration
  4. customdried

Sources & evidence

ORD record
ord-58b986704ff846cdbed53a10946384f6
Source dataset
uspto-grants-1985_08
Patent number
US04533731

Reaction notes

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