反应详情

3.5 g of ethyl 3-(4-fluorobenzoylamino)-3-isovalerylpropionate, 20 ml of dimethylformamide and 4.1 g of phosphorus oxychloride are treated in the same manner as described in Example 1. 2.5 g of ethyl 2-[2-(4-fluorophenyl)-5-isobutyl-4-oxazolyl]acetate are thereby obtained. Yield: 75.5%.