反应详情

4-Hydroxybenzofuran (1.3 g, 0.0097 M), ethyl 6-bromohexanoate (2.17 g, 0.0097 M), anhydrous potassium carbonate (1.44 g), sodium iodide (60 mg) and 95% ethanol (10 ml) were reacted together to give ethyl 6-(4-benzofuranyloxy)-hexanoate which was subsequently hydrolysed, as previously described for the preparation of 5-(4-benzofuranyloxy)pentanoic awcid, to give 6-(4-benzofuranyloxy)hexanoic acid, m.p. 86°-87° C. (Found: C, 67.54; H. 6.48. C14H16O4 requires C, 67.73; H. 6.50%).