反应详情

A solution of 1.1 ml (10.8 mmols) of 30% hydrogen peroxide and 1.1 gm (10 mmols) of selenium dioxide in 5 ml of water was added dropwise, while stirring, to a solution of 2.53 gm (10 mmols) of (E)-2-[(amino)phenylmethylene]-benzo[b]thiophen-3(2H)-one in 20 ml of methanol. The reaction temperature was not allowed to exceed +25° C. After 20 minutes, the reaction mixture was diluted with 100 ml of water, the reaction product was separated by suction filtering and recrystallized from ethanol/ethyl acetate (1:1 v/v) using activated charcoal.

1. customto exceed +25° C
2. customthe reaction product was separated by suction
3. filtrationfiltering
4. customrecrystallized from ethanol/ethyl acetate (1:1 v/v)