Hydrogen Peroxide → HCID 178510499, compound

HRID 485267Notes

Reaction equation

HRID 485267 reaction equation
[OH:1]O.[Se](=O)=O.[NH2:6]/[C:7](/[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[C:8]1\[C:9](=[O:17])[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[S:12]\1>O.CO>[NH2:6]/[C:7](/[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[C:8]1\[C:9](=[O:17])[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[S:12]\1=[O:1]

Participants

6

Reactant 3

HCID 784Hydrogen PeroxideHCID 24007Selenium DioxideHCID 178510717HCID 178510717, compound

Product 1

HCID 178510499HCID 178510499, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent2×

Procedure

A solution of 1.1 ml (10.8 mmols) of 30% hydrogen peroxide and 1.1 gm (10 mmols) of selenium dioxide in 5 ml of water was added dropwise, while stirring, to a solution of 2.53 gm (10 mmols) of (E)-2-[(amino)phenylmethylene]-benzo[b]thiophen-3(2H)-one in 20 ml of methanol. The reaction temperature was not allowed to exceed +25° C. After 20 minutes, the reaction mixture was diluted with 100 ml of water, the reaction product was separated by suction filtering and recrystallized from ethanol/ethyl acetate (1:1 v/v) using activated charcoal.

Workup

  1. customto exceed +25° C
  2. customthe reaction product was separated by suction
  3. filtrationfiltering
  4. customrecrystallized from ethanol/ethyl acetate (1:1 v/v)

Sources & evidence

ORD record
ord-0907ecf303094914b003eab19897a376
Source dataset
uspto-grants-1985_08
Patent number
US04536402

Reaction notes

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