m-Chloroperbenzoic acid → 3-Cyano-8-hydroxydibenzo[b,f]thiepin-5-Oxide

HRID 485465Notes

Reaction equation

HRID 485465 reaction equation
[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[CH:12]=[CH:11][C:10]3[CH:13]=[C:14]([OH:17])[CH:15]=[CH:16][C:9]=3[S:8][C:7]=2[CH:18]=1)#[N:2].ClC1C=CC=C(C(OO)=[O:27])C=1>C(Cl)Cl>[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[CH:12]=[CH:11][C:10]3[CH:13]=[C:14]([OH:17])[CH:15]=[CH:16][C:9]=3[S:8](=[O:27])[C:7]=2[CH:18]=1)#[N:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 134903843-Cyano-8-hydroxydibenzo[b,f]thiepine

Product 1

HCID 134903853-Cyano-8-hydroxydibenzo[b,f]thiepin-5-Oxide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Suspend 50.2 mg. of 3-cyano-8-hydroxydibenzo[b,f]thiepine in 9 ml. of methylene chloride and add 40.6 mg. of m-chloroperbenzoic acid. Allow the mixture to stand at room temperature for 30 minutes. Separate the solids by filtration to obtain the title product (m.p., 241°-243° C.).

Workup

  1. customSeparate the solids
  2. filtrationby filtration

Sources & evidence

ORD record
ord-99ea53ce3589461f83a786116bfe841d
Source dataset
uspto-grants-1985_08
Patent number
US04536507

Reaction notes

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