HRID485969

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8917

1-Decanethiol

C10H22S

HCID11430

Potassium Carbonate

CK2O3

结构：O=C(O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(O)=NCCO

HCID178524541

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCSc1c(SCCCCCCCCCC)c(SCCCCCCCCCC)c(C(O)=NCCO)c(C(=O)O)c1SCCCCCCCCCC

HCID178443464

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

2 g (6.08 millimols) of tetrachlorophthalic acid N-2-hydroxyethylimide, 5.30 g (30.4 millimols) of n-decanethiol, 6.30 g (45.6 millimols) of potassium carbonate and 20 ml of N,N-dimethylformamide are stirred at 25° C. for 7 hours. The mixture is acidified and extracted with methylene chloride. After recrystallisation from n-hexane at 0° C., 3.75 g (70% of theory) of the title compound are obtained; melting point 57°-8° C.

WORKUP

后处理

extractionextracted with methylene chloride
customAfter recrystallisation from n-hexane at 0° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f1d9b95f187446bcaa47845f35563cf3
来源数据集: uspto-grants-1985_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04537977
来源说明: uspto-grants-1985_08

反应 SMILES

[OH:1][CH2:2][CH2:3][N:4]=[C:5]([OH:19])[C:6]1[C:7](=[C:11](Cl)[C:12](Cl)=[C:13](Cl)[C:14]=1Cl)[C:8]([OH:10])=[O:9].[CH2:20]([SH:30])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29].C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[OH:1][CH2:2][CH2:3][N:4]=[C:5]([OH:19])[C:6]1[C:7](=[C:11]([S:30][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[C:12]([S:30][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])=[C:13]([S:30][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[C:14]=1[S:30][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[C:8]([OH:10])=[O:9]