反应详情

温度

15 °C

17.4 g (0.1 mol) of N-carbamoyl-6-aminohexanoic acid are dissolved in 50 g of methanesulfonic acid and the solution is cooled to 15° C. 12 g (0.3 mol) of hydrogen peroxide (85% strength by weight) are added dropwise with cooling at such a rate that the internal temperature can be maintained between 15° and 20° C. The mixture is subsequently stirred at 18° C. for a further 10 minutes, then cooled down to 0° C. and adjusted to pH 3 with aqueous sodium hydroxide solution (33% strength by weight). 65 g of sodium hydroxide solution are used. After stirring for 20 minutes at 0° C. the precipitated peroxycarboxylic acid is filtered off with suction, washed with ice-water and dried at 40° C. under an aspirator vacuum.

1. temperaturewith cooling at such a rate that the internal temperature
2. temperaturecan be maintained between 15° and 20° C
3. temperaturecooled down to 0° C.
4. filtrationis filtered off with suction
5. washwashed with ice-water
6. customdried at 40° C. under an aspirator vacuum