56-03-1 → HCID 19095468, compound

HRID 486402Notes

Reaction equation

HRID 486402 reaction equation
CN(C)C=O.[C:6]([NH2:12])([NH2:11])=[N:7][C:8](N)=[NH:9].[CH2:13]([N:15]=[C:16]=[S:17])[CH3:14]>O>[NH2:12][C:6]1[N:7]=[C:8]([NH2:9])[N:15]([CH2:13][CH3:14])[C:16](=[S:17])[N:11]=1

Participants

5

Reactant 3

HCID 593956-03-1HCID 6228DimethylformamideHCID 10966Ethyl isothiocyanate

Product 1

HCID 19095468HCID 19095468, compoundYield 104.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

To 15 ml of dry dimethylformamide were dissolved 1.52 g of diguanide and 1.31 g of ethylisothiocyanate, and the solution was heated at 100° C. for 4 hours. After cooling, the solution was added to 60 ml of water to produce white precipitates, which subsequently was dried to obtain 2.7 g of the title compound having the characteristics of:

Workup

  1. temperatureAfter cooling
  2. customto produce white precipitates, which
  3. customsubsequently was dried

Sources & evidence

ORD record
ord-5c3277c045434c12aaf2fd23019c1c57
Source dataset
uspto-grants-1994_03
Patent number
US05292733

Reaction notes

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