56-03-1 → 1,3,5-Triazine-2(1H)-thione, 4,6-diamino-1-phenyl-

HRID 486403Notes

Reaction equation

HRID 486403 reaction equation
[C:1]([NH2:7])([NH2:6])=[N:2][C:3](N)=[NH:4].[C:8]1([N:14]=[C:15]=[S:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>CN(C)C=O>[NH2:7][C:1]1[N:2]=[C:3]([NH2:4])[N:14]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:15](=[S:16])[N:6]=1

Participants

4

Reactant 2

HCID 593956-03-1HCID 7673Phenyl Isothiocyanate

Product 1

HCID 122094641,3,5-Triazine-2(1H)-thione, 4,6-diamino-1-phenyl-Yield 93.4%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To 25 ml of dry dimethylformamide were dissolved 2.0 g of diguanide and 2.7 g of phenyl isothiocyanate and the solution was placed at 40°~50° C. for 30 minutes. The solution was added to 200 ml of ice water to produce white precipitates, which subsequently was filtered and dried to obtain 4.05 g of the title compound having the characteristics of:

Workup

  1. customto produce white precipitates, which
  2. filtrationsubsequently was filtered
  3. customdried

Sources & evidence

ORD record
ord-ade9981568eb4ef7a5db06a4b3f59386
Source dataset
uspto-grants-1994_03
Patent number
US05292733

Reaction notes

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