Pyridine → HCID 178513065, compound

HRID 486601Notes

Reaction equation

HRID 486601 reaction equation
[S:1]([C:5]1[CH:24]=[CH:23][C:8]([C:9](OC2C(F)=C(F)C(F)=C(F)C=2F)=[O:10])=[CH:7][CH:6]=1)(=[O:4])(=[O:3])[NH2:2].S(C1C=CC(C(Cl)=O)=CC=1)(=O)(=O)N.FC1C(O)=C(F)C(F)=C(F)C=1F.N1C=CC=CC=1.[NH2:56][C:57]([NH2:59])=[NH:58]>CO>[S:1]([C:5]1[CH:24]=[CH:23][C:8]([C:9]([NH:58][C:57]([NH2:59])=[NH:56])=[O:10])=[CH:7][CH:6]=1)(=[O:4])(=[O:3])[NH2:2]

Participants

7

Reactant 5

HCID 1049PyridineHCID 3520GuanidineHCID 13041PentafluorophenolHCID 70103404-Sulphamoylbenzoyl chlorideHCID 19096120HCID 19096120, compound

Product 1

HCID 178513065HCID 178513065, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

is obtained analogously to the procedure given in Example 1 from pentafluorophenyl 4-sulfamoylbenzoate, prepared from 4-sulfamoylbenzoyl chloride and pentafluorophenol in the presence of 1 mol of pyridine, with guanidine in methanol as reaction medium.

Workup

  1. customis obtained analogously to the procedure

Sources & evidence

ORD record
ord-0360803a0d0a416e8f441014b4121660
Source dataset
uspto-grants-1994_03
Patent number
US05292755

Reaction notes

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