Hydrochloric Acid → HCID 19096398, compound

HRID 486704Notes

Reaction equation

HRID 486704 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[OH:12])[CH:7]=O)([OH:3])=[O:2].[CH3:13][C:14](=[O:19])[CH2:15][C:16](=[O:18])[CH3:17].Cl>O1CCCC1>[C:1]([C:4]1[CH:5]=[C:6]([CH:7]=[C:15]([C:14](=[O:19])[CH3:13])[C:16](=[O:18])[CH3:17])[CH:9]=[CH:10][C:11]=1[OH:12])([OH:3])=[O:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 31261AcetylacetoneHCID 692265-Formylsalicylic acid

Product 1

HCID 19096398HCID 19096398, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
50 °C

Procedure

A mixture containing 2 g 3-carboxy-4-hydroxybenzaldehyde, 4 ml 2,4-pentanedione and 20 ml tetrahydrofuran was saturated with hydrogen chloride gas. The solution was stirred for 2.0 h at 50° C. and evaporated to dryness in vacuo. The residue was crystallized from ethyl ether, mp. 112°-114° C.

Workup

  1. customevaporated to dryness in vacuo
  2. customThe residue was crystallized from ethyl ether, mp. 112°-114° C.

Sources & evidence

ORD record
ord-2813233b7361415f8ec48bcab3bcfc35
Source dataset
uspto-grants-1994_03
Patent number
US05292771

Reaction notes

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