Potassium Iodide → HCID 67852072, compound

HRID 487553Notes

Reaction equation

HRID 487553 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([CH2:11][CH2:12][NH2:13])=[CH:10][C:5]=2[S:4](=[O:14])[CH2:3]1.Br[CH2:16][CH2:17][CH2:18][CH2:19][N:20]1[C:24](=[O:25])[C:23]2=[CH:26][CH:27]=[CH:28][CH:29]=[C:22]2[C:21]1=[O:30].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>CN(C)C=O>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([CH2:11][CH2:12][NH:13][CH2:16][CH2:17][CH2:18][CH2:19][N:20]3[C:24](=[O:25])[C:23]4=[CH:26][CH:27]=[CH:28][CH:29]=[C:22]4[C:21]3=[O:30])=[CH:10][C:5]=2[S:4](=[O:14])[CH2:3]1

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 93575N-(4-Bromobutyl)phthalimideHCID 67713555HCID 67713555, compound

Product 1

HCID 67852072HCID 67852072, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
60 °C

Procedure

In a round-bottomed flask, 2.2 mmol of 3-methyl-6-(2-aminoethyl)benzothiazolinone, obtained in the previous example, are dissolved in 20 ml of dimethyl-formamide in the presence of 2.4 mmol of N-(4-bromo-butyl)phthalimide, 6.6 mmol of potassium carbonate and a catalytic amount of potassium iodide. The mixture is left stirring at 60° C. for 6 hours. After cooling, the solvent is evaporated off and/or extracted with chloroform after adding water.

Workup

  1. waitThe mixture is left
  2. temperatureAfter cooling
  3. customthe solvent is evaporated off
  4. extractionextracted with chloroform
  5. additionafter adding water

Sources & evidence

ORD record
ord-20f9a95992344f02beb1b4cf36b3713b
Source dataset
uspto-grants-1994_03
Patent number
US05296477

Reaction notes

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