反应详情

温度

90 °C

3-Phenyl-1H-pyrazolo[4,3-c]pyridine (1.95 g) was suspended in 50 ml of dimethylformamide to which 2-bromoethylphthalimide (2.54) and K2CO3 (1.4 g) had been added. This mixture was stirred and warmed at 90° C. for 4 hours and then an additional 1.25 g of 2-bromoethylphthalimide and 0.7 g of K2CO3 were added. After 2 more hours another 0.60 g of 2-bromoethylphthalimide and 0.4 g of K2CO3 were added and stirring and heating were continued for an additional 90 minutes. At the end of this time, the reaction mixture was poured into H2O and the product filtered off and dried to give 2.63 of 3-phenyl-1-[2-(phthalimido)ethyl]-1H-pyrazolo[4,3-c]pyridine.

1. additionhad been added
2. stirringstirring
3. temperatureheating
4. filtrationthe product filtered off
5. customdried