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HRID487665

反应详情

EQUATION

反应方程式

HRID 487665 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc2c(c1)CCC(=COC(=O)c1ccccc1)C2=O
HCID53877965

2-[(Benzoyloxy)methylene]-3,4-dihydro-6-methoxy-1(2H)-naphthalenone

C19H16O4

结构：[H][H]
HCID178418361

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc2c(c1)CCC(C)C2=O
HCID11116844

6-methoxy-2-methyl-3,4-dihydro-2H-naphthalen-1-one

C12H14O2

收率 73.3%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[O]=[Pt]
催化剂HCID82844

Platinum oxide (PtO)

OPt

结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

2-Benzoyloxymethylene-6-methoxy-1-tetralone (4.6 g, 0.015 mole) was hydrogenated over platinum oxide (160 mg) in isopropyl alcohol (150 mL) at 55 psi in a Parr hydrogenation apparatus. After about 90 minutes hydrogen uptake ceased and the reaction was stopped. The catalyst was removed by filtration and the solvents were removed in vacuo. The title compound (2.0 g, 0.011 mole, 70% yield) was obtained after purification by flash chromatography [gradient 10:1 to 5:1 EtOAc:Hexanes].

WORKUP

后处理

  1. customThe catalyst was removed by filtration
  2. customthe solvents were removed in vacuo