1,2,3,4-Tetrahydro-1-naphthylamine → HCID 22742784, compound

HRID 48772Notes

Reaction equation

HRID 48772 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH2:5][CH:6]1[C:15]2[C:10](=[CH:11][C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=2)[CH2:9][CH2:8][NH:7]1.Br[CH2:26][C:27](Br)=[O:28].[CH:30]1([NH2:40])[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH2:33][CH2:32][CH2:31]1>>[Br:1][C:2]1[CH:3]=[C:4]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH2:5][CH:6]1[C:15]2[C:10](=[CH:11][C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=2)[CH2:9][CH2:8][N:7]1[CH2:26][C:27]([NH:40][CH:30]1[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH2:33][CH2:32][CH2:31]1)=[O:28]

Participants

4

Reactant 3

HCID 180661,2,3,4-Tetrahydro-1-naphthylamineHCID 61147Bromoacetyl bromideHCID 3661891-(3-Bromo-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 22742784HCID 22742784, compound

Procedure

prepared by reaction of 1-(3-Bromo-4-methoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 1,2,3,4-tetrahydro-1-naphthylamine

Sources & evidence

ORD record
ord-c99c4c0c752d4ada92eb11a8786afc3e
Source dataset
uspto-grants-2004_03
Patent number
US06703392B2

Reaction notes

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