反应详情

Thioacetamide (326.0 mg, 4.339 mmol) and 2-bromomethyl-naphthalene (959.0 mg, 4.337 mmol) were placed in a 50 mL round-bottom flask. 20 mL of CHCl3 were added and the mixure was refluxed for 3 h at which time a white precipitate formed. The mixture was cooled and the precipitate collected. The precipitate was washed with 20 mL of CH2Cl2 and placed under vacuum for drying to give 1.01 g of thioacetimidic acid naphthalen-2-ylmethyl ester hydrobromide salt as a fine white powder.

1. temperaturethe mixure was refluxed for 3 h at which time a white precipitate
2. customformed
3. temperatureThe mixture was cooled
4. customthe precipitate collected
5. washThe precipitate was washed with 20 mL of CH2Cl2
6. customfor drying