反应详情

Indole 3-carboxylic acid, (2.0 g) was dissolved in 5 ml of SOCl2. The mixture was heated to reflux for 30 minutes. Removal of excess of SOCl2 under vacuum provided intermediate 9, indole 3-carbonyl chloride, which was carried to the next step without further purification.

1. temperatureThe mixture was heated
2. temperatureto reflux for 30 minutes
3. customRemoval of excess of SOCl2 under vacuum