Triethylamine → HCID 66593512, compound

HRID 495168Notes

Reaction equation

HRID 495168 reaction equation
[CH3:1][C:2]1[CH:6]([CH3:7])[CH:5]=[C:4]([CH3:8])[C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH2:15].C(N(CC)CC)C.[C:23](Cl)(=[O:28])[C:24]([CH3:27])([CH3:26])[CH3:25]>>[CH3:1][C:2]1[CH:6]([CH3:7])[CH:5]=[C:4]([CH3:8])[C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:15][C:23](=[O:28])[C:24]([CH3:27])([CH3:26])[CH3:25]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 62493Pivaloyl chlorideHCID 66593931HCID 66593931, compound

Product 1

HCID 66593512HCID 66593512, compoundYield 89%

Procedure

An experiment was performed in the same manner as in Example 49 using 0.534 g (2.68 mmol) of 2-(2,3,5-trimethylcyclopenta-1,4-dienyl)phenylamine, 0.325 g (3.22 mmol) of triethylamine, and 0.388 g (3.22 mmol) of pivaloyl chloride. The reaction product was purified using a column chromatography with a hexane/ethylacetate (v/v, 5:1) solvent. The purified product was dried in vacuum to remove the solvent therein, thereby obtaining while solid (0.674 g, 89%).

Workup

  1. customThe reaction product was purified
  2. customThe purified product was dried in vacuum
  3. customto remove the solvent

Sources & evidence

ORD record
ord-fede89a18d7c4f2d932342bed22e679a
Source dataset
uspto-grants-2009_05
Patent number
US07538239B2

Reaction notes

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