反应详情

温度

5 °C

13.1 g of triphenyphosphine are added to a solution of 8.2 g of 3-picolyl chloride hydrochloride in 120 ml of dimethylformamide. After stirring for 5 minutes, the mixture is heated at reflux for 30 minutes in a microwave apparatus and then cooled to 5° C. The crystals obtained are filtered off, rinsed with dimethylformamide and then with ether, and dried under reduced pressure, allowing the expected product to be isolated.

1. temperaturethe mixture is heated
2. temperatureat reflux for 30 minutes in a microwave apparatus
3. customThe crystals obtained
4. filtrationare filtered off
5. washrinsed with dimethylformamide
6. dry with materialwith ether, and dried under reduced pressure
7. customto be isolated