Potassium Iodide → HCID 70142752, compound

HRID 496070Notes

Reaction equation

HRID 496070 reaction equation
Br[CH2:2][C:3]1([N:6]([CH3:14])[C:7](=[O:13])[O:8][C:9]([CH3:12])([CH3:11])[CH3:10])[CH2:5][CH2:4]1.[C-:15]#[N:16].[K+].[I-].[K+].C(=O)([O-])[O-].[Na+].[Na+]>CS(C)=O.O>[C:15]([CH2:2][C:3]1([N:6]([CH3:14])[C:7](=[O:13])[O:8][C:9]([CH3:12])([CH3:11])[CH3:10])[CH2:5][CH2:4]1)#[N:16]

Participants

7

Reactant 4

HCID 4875Potassium IodideHCID 9032Potassium CyanideHCID 10340Sodium CarbonateHCID 70144582HCID 70144582, compound

Product 1

HCID 70142752HCID 70142752, compound

Reagents, catalysts & solvents 2

HCID 679Dimethyl SulfoxideSolventHCID 962WaterSolvent

Conditions

Temperature
70 °C

Procedure

A mixture containing 26.4 g of the product of Step 1, 26 g of potassium cyanide and 2.6 g of potassium iodide in 264 ml of dimethyl sulphoxide is stirred at 70° C. for 20 hours. The mixture is cooled and 400 ml of 10% sodium carbonate in water are added. After extraction with ether and customary treatment, evaporation of the residue under reduced pressure allows the expected product to be isolated.

Workup

  1. temperatureThe mixture is cooled
  2. extractionAfter extraction
  3. customwith ether and customary treatment, evaporation of the residue under reduced pressure
  4. customto be isolated

Sources & evidence

ORD record
ord-bce5ee0717b84928912e06d7d6e8fba0
Source dataset
uspto-grants-2005_09
Patent number
US06943184B2

Reaction notes

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