Ethyl formate → 5,7-Dibromo-1,2-dihydro-1,2,4-benzothiadiazine-1,1-dioxide

HRID 496139Notes

Reaction equation

HRID 496139 reaction equation
[NH2:1][C:2]1[C:7]([Br:8])=[CH:6][C:5]([Br:9])=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].[CH3:14]COC=O>C(N(CC)CC)C>[Br:8][C:7]1[C:2]2[N:1]=[CH:14][NH:13][S:10](=[O:12])(=[O:11])[C:3]=2[CH:4]=[C:5]([Br:9])[CH:6]=1

Participants

4

Reactant 2

HCID 8025Ethyl formateHCID 12013962-Amino-3,5-dibromobenzenesulfonamide2×

Product 1

HCID 1785271715,7-Dibromo-1,2-dihydro-1,2,4-benzothiadiazine-1,1-dioxide

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Amino-3,5-dibromobenzenesulfonamide (see compound 125) was transformed by Method G (using ethylformiat and a catalytic amount of triethylamine). M.p. 289-292° C.

Sources & evidence

ORD record
ord-c23554bd11884496adcc957179d65019
Source dataset
uspto-grants-2005_09
Patent number
US06943159B1

Reaction notes

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