Hydrochloric Acid → HCID 178450153, compound

HRID 496798Notes

Reaction equation

HRID 496798 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11]1[CH:16]=[CH:15][C:14]([NH:17][C:18](=[O:34])[CH:19]([O:23][C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([C:30](=[NH:33])[NH:31][OH:32])[CH:25]=2)[CH2:20][CH2:21][CH3:22])=[CH:13][CH:12]=1)(=[O:4])=[O:3].[ClH:35]>CO.C(O)(C)C>[ClH:35].[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11]1[CH:12]=[CH:13][C:14]([NH:17][C:18](=[O:34])[CH:19]([O:23][C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([C:30](=[NH:33])[NH:31][OH:32])[CH:25]=2)[CH2:20][CH2:21][CH3:22])=[CH:15][CH:16]=1)(=[O:3])=[O:4]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 178450152HCID 178450152, compound

Product 1

HCID 178450153HCID 178450153, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 3776IsopropanolSolvent

Procedure

A solution of 100 mg (0.208 mmol) of 2-[3-(N-hydroxycarbamimidoyl)phenoxy]pentanoic acid (2′-methanesulfonylbiphenyl-4-yl)amide in 5 ml of methanol is treated with 2.08 ml of a 0.1 N solution of hydrogen chloride in isopropanol. The solution is evaporated. A colourless solid is obtained; FAB 482

Workup

  1. customThe solution is evaporated
  2. customA colourless solid is obtained

Sources & evidence

ORD record
ord-86d974792f62440289f9c63f47412ba2
Source dataset
uspto-grants-2005_09
Patent number
US06946489B2

Reaction notes

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