反应详情

3 g of 5-benzoyloxy-1-chloro-2-hydroxybenzene were dissolved in 35 ml of DMF. 2.17 g of sodium iodide and 3.29 g of chloramin T were added. After one hour of stirring at room temperature, about 500 ml of water were added to the mixture, which was then extracted with ethyl acetate. The organic phase was washed with 5% strength sodium thiosulfate solution, dried and concentrated using a rotary evaporator. The resulting product was clean enough for the next reaction. Yield: 3.81 g (84%)

1. extractionwas then extracted with ethyl acetate
2. washThe organic phase was washed with 5% strength sodium thiosulfate solution
3. customdried
4. concentrationconcentrated
5. customa rotary evaporator
6. customThe resulting product was clean enough for the next reaction