反应详情

A mixture of 4-acetamido-2-fluorobenzenesulfonamide (11.15 g, 48 mmol) and sodium hydroxide (11.5 g, 480 mmol) in water (80 mL) was heated at reflux temperature for 3 hours. The mixture was made neutral by addition of 2N—HCl solution, and resulting suspension was filtered to give the subtitle compound (5.8 g, 63.5% yield).

1. temperaturewas heated
2. temperatureat reflux temperature for 3 hours
3. customresulting suspension
4. filtrationwas filtered