Hydrochloric Acid → HCID 23393476, compound

HRID 498143Notes

Reaction equation

HRID 498143 reaction equation
Cl.[CH:2]1([CH2:8][CH2:9][C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]2([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)OCC[O:18]2)=[O:11])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.CCCCCCC.CCOCC>C1COCC1>[CH:2]1([CH2:8][CH2:9][C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17](=[O:18])[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[O:11])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 21897273Diethylether heptaneHCID 22320911HCID 22320911, compound

Product 1

HCID 23393476HCID 23393476, compoundYield 60%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

This compound was synthesised as described under 1.e) with 2.0 ml of a 1N solution of HCl, 4.12 g (11.4 mmol) of 4-(2-phenyl-1,3-dioxolan-2-yl)butyl 3-cyclohexylpropionate obtained under a) in 20 ml of THF for 19 h. Column chromatography (SiO2, heptane/ether 3:2) afforded 2.15 g (60%) of a yellow oil containing small amounts of impurities, which can be distilled off (Kugelrohr, 150° C./1×102 Pa).

Workup

  1. customThis compound was synthesised

Sources & evidence

ORD record
ord-08989cca380649908deadf9dd7642df1
Source dataset
uspto-grants-2005_09
Patent number
US06949680B2

Reaction notes

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