反应详情

2 ml of TFA are added to a solution of 0.84 g of the compound obtained in step 5.3, in 2 ml of DCM. The medium is stirred at AT for 6 h. The medium is evaporated, taken up several times in DCM, and evaporated so as to entrain the TFA. The medium is taken up in DCM and then treated with a 10% NH4OH solution. The organic phase is dried over MgSO4 and then evaporated, to give 0.15 g of the expected product.

1. customThe medium is evaporated
2. customevaporated so as
3. additiontreated with a 10% NH4OH solution
4. dry with materialThe organic phase is dried over MgSO4
5. customevaporated