反应详情

A mixture of methyl thiosalicylate (1.01 g, 6.0 mmol), 2-furonitrile (0.57 g, 6.0 mmol), triethylamine (1.5 ml, 10.7 mmol) and toluene (20 ml) was refluxed for 24 hrs. After cooling, the precipitated crystals were collected by filtration and recrystallized from hexane-ethanol to give the titled compound (0.26 g, 19%).

1. temperaturewas refluxed for 24 hrs
2. temperatureAfter cooling
3. filtrationthe precipitated crystals were collected by filtration
4. customrecrystallized from hexane-ethanol