Diisopropyl Ether → HCID 22939382, compound

HRID 499546Notes

Reaction equation

HRID 499546 reaction equation
[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[S:5][C:4]([C:12]2[N:17]=[C:16]([S:18]([CH2:20][C:21]([O:23]C(C)(C)C)=[O:22])=[O:19])[CH:15]=[CH:14][CH:13]=2)=[N:3]1.C(OC(C)C)(C)C>FC(F)(F)C(O)=O>[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[S:5][C:4]([C:12]2[N:17]=[C:16]([S:18]([CH2:20][C:21]([OH:23])=[O:22])=[O:19])[CH:15]=[CH:14][CH:13]=2)=[N:3]1

Participants

4

Reactant 2

HCID 7914Diisopropyl EtherHCID 59750212HCID 59750212, compound

Product 1

HCID 22939382HCID 22939382, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

tert-Butyl {[6-(4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]sulfinyl}acetate (0.12 g, 0.30 mmol) was dissolved in trifluoroacetic acid (5 ml), and the mixture was stirred for 0.5 hr. Diisopropyl ether was added to the mixture. The obtained crystals were recrystallized from ethanol to give the titled compound (0.081 g, 79%) as pale yellow crystals.

Workup

  1. customThe obtained crystals were recrystallized from ethanol

Sources & evidence

ORD record
ord-080a190be0e0490cbf39532a4c5a2895
Source dataset
uspto-grants-2010_08
Patent number
US07767665B2

Reaction notes

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