HRID499965

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6456

Trityl chloride

C19H15Cl

结构：COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]2[C@@H](C)[C@@H](O)C[C@H]12

HCID87691

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]2[C@@H](C)[C@@H](O)C[C@H]12

HCID76311846

未命名化合物

收率 65%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

CONDITIONS

反应条件

温度: 45 °C

PROCEDURE

实验过程

The loganin was dissolved in pyridine and trityl chloride was added in 1.5 equivalents and stirred at 45° C. for 36 hrs to give the compound 6′-O-trityl loganin (2) in 65% yield.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b864c44cdb7348928c91aa95dd0aac9b
来源数据集: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07767798B2
来源说明: uspto-grants-2010_08

反应 SMILES

[CH3:1][C@@H:2]1[C@H:6]2[C@H:7]([O:15][C@@H:16]3[O:21][C@H:20]([CH2:22][OH:23])[C@@H:19]([OH:24])[C@H:18]([OH:25])[C@H:17]3[OH:26])[O:8][CH:9]=[C:10]([C:11]([O:13][CH3:14])=[O:12])[C@H:5]2[CH2:4][C@@H:3]1[OH:27].[C:28](Cl)([C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)([C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>N1C=CC=CC=1>[CH3:1][C@@H:2]1[C@H:6]2[C@H:7]([O:15][C@@H:16]3[O:21][C@H:20]([CH2:22][O:23][C:28]([C:29]4[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=4)([C:41]4[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=4)[C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=4)[C@@H:19]([OH:24])[C@H:18]([OH:25])[C@H:17]3[OH:26])[O:8][CH:9]=[C:10]([C:11]([O:13][CH3:14])=[O:12])[C@H:5]2[CH2:4][C@@H:3]1[OH:27]