反应详情

4-Methoxy-3-nitrophenylacetate (2.46 g, 11.7 mmol) was dissolved in anhydrous ethanol (80 ml) and sodium ethoxide (1.19 g, 17.5 mmol) was added. The reaction was stirred at room temperature for 0.5 h. The dark red solution was acidified with 2M HCl and concentrated under reduced pressure. The residue was taken up into water and extracted with dichloromethane. The combined organics were washed with 2M HCl and brine, then dried over sodium sulfate. Evaporation of the solvent under reduced pressure gave the title compound as a yellow solid.

1. concentrationconcentrated under reduced pressure
2. extractionextracted with dichloromethane
3. washThe combined organics were washed with 2M HCl and brine
4. dry with materialdried over sodium sulfate
5. customEvaporation of the solvent under reduced pressure