Aniline → HCID 13435884, compound

HRID 502954Notes

Reaction equation

HRID 502954 reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[C:9]([CH3:16])([CH3:15])[C:10]([O:12][CH2:13][CH3:14])=[O:11].C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[NH:1]([C:9]([CH3:16])([CH3:15])[C:10]([O:12][CH2:13][CH3:14])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 6115Aniline

HCID 11430Potassium Carbonate

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl ester

Product 1

HCID 13435884HCID 13435884, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Aniline, ethyl 2-bromoisobutyrate and potassium carbonate were reacted in DMF at 90° C. to obtain ethyl 2-anilino-2-methylpropanoate.

Sources & evidence

ORD record: ord-57e85ae98dc44f26a3b0794db3f8e177
Source dataset: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07776897B2

Reaction notes

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