反应详情

温度

100 °C

100 mg 4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde (prepared as described for example 1) are dissolved in 2 ml THF and 1 ml of a 2M solution of MeZnCl is added. The mixture is heated (100° C., microwave) for 2 h, cooled to room temperature and extracted with a mixture of dichloromethane and water. The organic layers are dried over sodium sulphate and the solvent is evaporated.

1. temperaturecooled to room temperature
2. extractionextracted with a mixture of dichloromethane and water
3. dry with materialThe organic layers are dried over sodium sulphate
4. customthe solvent is evaporated