反应详情

3-[4-(2-Cyano-benzenesulfonyl)-2-methoxy-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester was deprotected following the procedure described in Example 1. The free amine base was converted in the corresponding hydrochloride salt by addition of a small excess of HCl in 1,4-dioxane: MP=247.8-249.1° C.